Anti-coagulant protein 5
Intermolecular
Cysteine 261 of Coagulation factor X and cysteine 65
Cysteine 415 of Coagulation factor X and cysteine 38
Cysteine 261 of Coagulation factor X and cysteine 38
Cysteine 443 of Coagulation factor X and cysteine 38
Cysteine 277 of Coagulation factor X and cysteine 65
Cysteine 415 of Coagulation factor X and cysteine 65
2p3f H 42 N 42
A redox-regulated disulphide may form between cysteine 261 of Coagulation factor X and cysteine 65 of Anti-coagulant protein 5 (42 and 42 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
2p3f
Structure name
crystal structure of the factor xa/nap5 complex
Structure deposition date
2007-03-08
Thiol separation (Å)
8
Half-sphere exposure sum ?
97
Minimum pKa ?
nan
% buried
nan
Peptide A name
Coagulation factor X
Peptide B name
Anti-coagulant protein 5
Peptide A accession
P00742
Peptide B accession
Q16940
Peptide A residue number
261
Peptide B residue number
65
Ligandability
Cysteine 261 of Coagulation factor X
Cysteine 65 of Anti-coagulant protein 5
2p3f H 191 N 15
A redox-regulated disulphide may form between cysteine 415 of Coagulation factor X and cysteine 38 of Anti-coagulant protein 5 (191 and 15 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
2p3f
Structure name
crystal structure of the factor xa/nap5 complex
Structure deposition date
2007-03-08
Thiol separation (Å)
8
Half-sphere exposure sum ?
94
Minimum pKa ?
nan
% buried
nan
Peptide A name
Coagulation factor X
Peptide B name
Anti-coagulant protein 5
Peptide A accession
P00742
Peptide B accession
Q16940
Peptide A residue number
415
Peptide B residue number
38
Ligandability
Cysteine 415 of Coagulation factor X
Cysteine 38 of Anti-coagulant protein 5
2p3f H 42 N 15
A redox-regulated disulphide may form between cysteine 261 of Coagulation factor X and cysteine 38 of Anti-coagulant protein 5 (42 and 15 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
2p3f
Structure name
crystal structure of the factor xa/nap5 complex
Structure deposition date
2007-03-08
Thiol separation (Å)
9
Half-sphere exposure sum ?
91
Minimum pKa ?
nan
% buried
nan
Peptide A name
Coagulation factor X
Peptide B name
Anti-coagulant protein 5
Peptide A accession
P00742
Peptide B accession
Q16940
Peptide A residue number
261
Peptide B residue number
38
Ligandability
Cysteine 261 of Coagulation factor X
Cysteine 38 of Anti-coagulant protein 5
2p3f H 220 N 15
A redox-regulated disulphide may form between cysteine 443 of Coagulation factor X and cysteine 38 of Anti-coagulant protein 5 (220 and 15 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
2p3f
Structure name
crystal structure of the factor xa/nap5 complex
Structure deposition date
2007-03-08
Thiol separation (Å)
10
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide A name
Coagulation factor X
Peptide B name
Anti-coagulant protein 5
Peptide A accession
P00742
Peptide B accession
Q16940
Peptide A residue number
443
Peptide B residue number
38
Ligandability
Cysteine 443 of Coagulation factor X
Cysteine 38 of Anti-coagulant protein 5
2p3f H 58 N 42
A redox-regulated disulphide may form between cysteine 277 of Coagulation factor X and cysteine 65 of Anti-coagulant protein 5 (58 and 42 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
33
PDB code
2p3f
Structure name
crystal structure of the factor xa/nap5 complex
Structure deposition date
2007-03-08
Thiol separation (Å)
10
Half-sphere exposure sum ?
94
Minimum pKa ?
nan
% buried
nan
Peptide A name
Coagulation factor X
Peptide B name
Anti-coagulant protein 5
Peptide A accession
P00742
Peptide B accession
Q16940
Peptide A residue number
277
Peptide B residue number
65
Ligandability
Cysteine 277 of Coagulation factor X
Cysteine 65 of Anti-coagulant protein 5
2p3f H 191 N 42
A redox-regulated disulphide may form between cysteine 415 of Coagulation factor X and cysteine 65 of Anti-coagulant protein 5 (191 and 42 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
2p3f
Structure name
crystal structure of the factor xa/nap5 complex
Structure deposition date
2007-03-08
Thiol separation (Å)
10
Half-sphere exposure sum ?
100
Minimum pKa ?
nan
% buried
nan
Peptide A name
Coagulation factor X
Peptide B name
Anti-coagulant protein 5
Peptide A accession
P00742
Peptide B accession
Q16940
Peptide A residue number
415
Peptide B residue number
65
Ligandability
Cysteine 415 of Coagulation factor X
Cysteine 65 of Anti-coagulant protein 5
If this tool was useful for finding a disulphide, please cite: