a tool for identifying drug-targetable redox-active disulphides

HCG15971, isoform CRA_a

Intramolecular

Cysteine 217 and cysteine 257

A redox-regulated disulphide may form within HCG15971, isoform CRA_a between cysteines 217 and 257.

Details

Redox score ?

69

PDB code

Structure name

model of actin-fimbrin abd2 complex

Structure deposition date

2008-01-16

Thiol separation (Å)

4

Half-sphere exposure sum ?

79

Minimum pK_a ?

8

% buried

100

Peptide accession

Residue number A

217

Residue number B

257

Peptide name

HCG15971, isoform CRA_a

Ligandability

Cysteine 217 of HCG15971, isoform CRA_a

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 257 of HCG15971, isoform CRA_a

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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