tRNA pseudouridine synthase Pus10
Intramolecular
Cysteine 230 and cysteine 233
Cysteine 24 and cysteine 109
Cysteine 21 and cysteine 24
Cysteine 24 and cysteine 112
Cysteine 21 and cysteine 109
Cysteine 21 and cysteine 112
Cysteine 24 and cysteine 120
Cysteine 112 and cysteine 276
Cysteine 21 and cysteine 120
Cysteine 112 and cysteine 120
More...Cysteine 129 and cysteine 283
Cysteine 109 and cysteine 112
2v9k A 230 A 233
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 230 and 233.
Details
Redox score ?
85
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
0
Peptide accession
Q3MIT2
Residue number A
230
Residue number B
233
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 230 of tRNA pseudouridine synthase Pus10
Cysteine 233 of tRNA pseudouridine synthase Pus10
2v9k A 24 A 109
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 24 and 109.
Details
Redox score ?
80
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
5
% buried
nan
Peptide accession
Q3MIT2
Residue number A
24
Residue number B
109
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 24 of tRNA pseudouridine synthase Pus10
Cysteine 109 of tRNA pseudouridine synthase Pus10
2v9k A 21 A 24
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 21 and 24.
Details
Redox score ?
77
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
82
Minimum pKa ?
5
% buried
100
Peptide accession
Q3MIT2
Residue number A
21
Residue number B
24
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 21 of tRNA pseudouridine synthase Pus10
Cysteine 24 of tRNA pseudouridine synthase Pus10
2v9k A 24 A 112
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 24 and 112.
Details
Redox score ?
75
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
92
Minimum pKa ?
5
% buried
100
Peptide accession
Q3MIT2
Residue number A
24
Residue number B
112
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 24 of tRNA pseudouridine synthase Pus10
Cysteine 112 of tRNA pseudouridine synthase Pus10
2v9k A 21 A 109
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 21 and 109. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
15
% buried
nan
Peptide accession
Q3MIT2
Residue number A
21
Residue number B
109
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 21 of tRNA pseudouridine synthase Pus10
Cysteine 109 of tRNA pseudouridine synthase Pus10
2v9k A 21 A 112
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 21 and 112. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
85
Minimum pKa ?
15
% buried
100
Peptide accession
Q3MIT2
Residue number A
21
Residue number B
112
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 21 of tRNA pseudouridine synthase Pus10
Cysteine 112 of tRNA pseudouridine synthase Pus10
2v9k A 24 A 120
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 24 and 120. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
79
Minimum pKa ?
5
% buried
100
Peptide accession
Q3MIT2
Residue number A
24
Residue number B
120
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 24 of tRNA pseudouridine synthase Pus10
Cysteine 120 of tRNA pseudouridine synthase Pus10
2v9k A 112 A 276
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 112 and 276. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
8
Half-sphere exposure sum ?
83
Minimum pKa ?
12
% buried
86
Peptide accession
Q3MIT2
Residue number A
112
Residue number B
276
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 112 of tRNA pseudouridine synthase Pus10
Cysteine 276 of tRNA pseudouridine synthase Pus10
2v9k A 21 A 120
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 21 and 120. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
11
% buried
100
Peptide accession
Q3MIT2
Residue number A
21
Residue number B
120
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 21 of tRNA pseudouridine synthase Pus10
Cysteine 120 of tRNA pseudouridine synthase Pus10
2v9k A 112 A 120
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 112 and 120. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
8
Half-sphere exposure sum ?
84
Minimum pKa ?
11
% buried
100
Peptide accession
Q3MIT2
Residue number A
112
Residue number B
120
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 112 of tRNA pseudouridine synthase Pus10
Cysteine 120 of tRNA pseudouridine synthase Pus10
2v9k A 129 A 283
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 129 and 283. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
10
Half-sphere exposure sum ?
66
Minimum pKa ?
10
% buried
48
Peptide accession
Q3MIT2
Residue number A
129
Residue number B
283
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 129 of tRNA pseudouridine synthase Pus10
Cysteine 283 of tRNA pseudouridine synthase Pus10
2v9k A 109 A 112
A redox-regulated disulphide may form within tRNA pseudouridine synthase Pus10 between cysteines 109 and 112. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
2v9k
Structure name
crystal structure of human pus10, a novel pseudouridine synthase
Structure deposition date
2007-08-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
24
% buried
nan
Peptide accession
Q3MIT2
Residue number A
109
Residue number B
112
Peptide name
tRNA pseudouridine synthase Pus10
Ligandability
Cysteine 109 of tRNA pseudouridine synthase Pus10
Cysteine 112 of tRNA pseudouridine synthase Pus10
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