T-cell immunoreceptor with Ig and ITIM domains
7vyt T 45 T 108
A redox-regulated disulphide may form within T-cell immunoreceptor with Ig and ITIM domains between cysteines 45 and 108.
Details
Redox score ?
75
PDB code
7vyt
Structure name
crystal structure of human tigit(23-129) in complex with the scfv fragment of anti-tigit antibody mg1131
Structure deposition date
2021-11-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
8
% buried
78
Peptide accession
Q495A1
Residue number A
45
Residue number B
108
Peptide name
T-cell immunoreceptor with Ig and ITIM domains
Ligandability
Cysteine 45 of T-cell immunoreceptor with Ig and ITIM domains
Cysteine 108 of T-cell immunoreceptor with Ig and ITIM domains
7vyt T 69 T 108
A redox-regulated disulphide may form within T-cell immunoreceptor with Ig and ITIM domains between cysteines 69 and 108. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
7vyt
Structure name
crystal structure of human tigit(23-129) in complex with the scfv fragment of anti-tigit antibody mg1131
Structure deposition date
2021-11-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
76
Minimum pKa ?
11
% buried
68
Peptide accession
Q495A1
Residue number A
69
Residue number B
108
Peptide name
T-cell immunoreceptor with Ig and ITIM domains
Ligandability
Cysteine 69 of T-cell immunoreceptor with Ig and ITIM domains
Cysteine 108 of T-cell immunoreceptor with Ig and ITIM domains
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