Synaptic vesicle glycoprotein 2C

Intramolecular

A redox-regulated disulphide may form within Synaptic vesicle glycoprotein 2C between cysteines 520 and 560. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4jra

Structure name

crystal structure of the botulinum neurotoxin a receptor-binding domain in complex with the luminal domain of sv2c

Structure deposition date

2013-03-21

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q496J9

Residue number A

520

Residue number B

560

Peptide name

Synaptic vesicle glycoprotein 2C

Ligandability

Cysteine 520 of Synaptic vesicle glycoprotein 2C

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.