ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

NAD kinase 2, mitochondrial

Intramolecular
Cysteine 404 and cysteine 408
A redox-regulated disulphide may form within NAD kinase 2, mitochondrial between cysteines 404 and 408. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
7n29
Structure name
structure of nad kinase
Structure deposition date
2021-05-28
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
10
% buried
60
Peptide accession
Q4G0N4
Residue number A
404
Residue number B
408
Peptide name
NAD kinase 2, mitochondrial

Ligandability

Cysteine 404 of NAD kinase 2, mitochondrial

Cysteine 408 of NAD kinase 2, mitochondrial

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