Programmed cell death protein 4

Intramolecular

A redox-regulated disulphide may form within Programmed cell death protein 4 between cysteines 227 and 275. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

2kzt

Structure name

structure of the tandem ma-3 region of pdcd4

Structure deposition date

2010-06-24

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q53EL6

Residue number A

227

Residue number B

275

Peptide name

Programmed cell death protein 4

Ligandability

Cysteine 227 of Programmed cell death protein 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 275 of Programmed cell death protein 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Programmed cell death protein 4 between cysteines 433 and 447. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?