a tool for identifying drug-targetable redox-active disulphides

Endoribonuclease LACTB2

Intramolecular

Cysteine 21 and cysteine 58

A redox-regulated disulphide may form within Endoribonuclease LACTB2 between cysteines 21 and 58.

Details

Redox score ?

70

PDB code

Structure name

crystal structure of human lactb2

Structure deposition date

2011-12-22

Thiol separation (Å)

4

Half-sphere exposure sum ?

75

Minimum pK_a ?

8

% buried

78

Peptide accession

Residue number A

21

Residue number B

58

Peptide name

Endoribonuclease LACTB2

Ligandability

Cysteine 21 of Endoribonuclease LACTB2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 58 of Endoribonuclease LACTB2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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