Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Intramolecular
Cysteine 100 and cysteine 111
Cysteine 410 and cysteine 438
Cysteine 248 and cysteine 410
Cysteine 401 and cysteine 410
Cysteine 95 and cysteine 100
Cysteine 248 and cysteine 438
Cysteine 248 and cysteine 249
Cysteine 95 and cysteine 111
Cysteine 401 and cysteine 438
Cysteine 248 and cysteine 401
More...Cysteine 249 and cysteine 410
Cysteine 249 and cysteine 451
3rbf A 100 A 111
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 100 and 111. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
6
Half-sphere exposure sum ?
68
Minimum pKa ?
11
% buried
73
Peptide accession
Q53Y41
Residue number A
100
Residue number B
111
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 100 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 111 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf B 410 B 438
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 410 and 438. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
5
Half-sphere exposure sum ?
71
Minimum pKa ?
11
% buried
82
Peptide accession
Q53Y41
Residue number A
410
Residue number B
438
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 410 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 438 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf B 248 B 410
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 248 and 410. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
5
Half-sphere exposure sum ?
87
Minimum pKa ?
11
% buried
88
Peptide accession
Q53Y41
Residue number A
248
Residue number B
410
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 248 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 410 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf B 401 B 410
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 401 and 410. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
77
Minimum pKa ?
10
% buried
83
Peptide accession
Q53Y41
Residue number A
401
Residue number B
410
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 401 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 410 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf A 95 A 100
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 95 and 100. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
69
Minimum pKa ?
12
% buried
92
Peptide accession
Q53Y41
Residue number A
95
Residue number B
100
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 95 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 100 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf B 248 B 438
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 248 and 438. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
71
Minimum pKa ?
11
% buried
73
Peptide accession
Q53Y41
Residue number A
248
Residue number B
438
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 248 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 438 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf B 248 B 249
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 248 and 249. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
79
Minimum pKa ?
11
% buried
90
Peptide accession
Q53Y41
Residue number A
248
Residue number B
249
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 248 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 249 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf B 95 B 111
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 95 and 111. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
72
Minimum pKa ?
11
% buried
90
Peptide accession
Q53Y41
Residue number A
95
Residue number B
111
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 95 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 111 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf A 401 A 438
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 401 and 438. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
8
Half-sphere exposure sum ?
62
Minimum pKa ?
11
% buried
66
Peptide accession
Q53Y41
Residue number A
401
Residue number B
438
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 401 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 438 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf A 248 A 401
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 248 and 401. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
10
Half-sphere exposure sum ?
77
Minimum pKa ?
10
% buried
70
Peptide accession
Q53Y41
Residue number A
248
Residue number B
401
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 248 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 401 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf A 249 A 410
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 249 and 410. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
8
Half-sphere exposure sum ?
78
Minimum pKa ?
13
% buried
98
Peptide accession
Q53Y41
Residue number A
249
Residue number B
410
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 249 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 410 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
3rbf B 249 B 451
A redox-regulated disulphide may form within Dopa decarboxylase (Aromatic L-amino acid decarboxylase) between cysteines 249 and 451. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
3rbf
Structure name
crystal structure of human aromatic l-amino acid decarboxylase (aadc) in the apo form
Structure deposition date
2011-03-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
82
Minimum pKa ?
11
% buried
100
Peptide accession
Q53Y41
Residue number A
249
Residue number B
451
Peptide name
Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Ligandability
Cysteine 249 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
Cysteine 451 of Dopa decarboxylase (Aromatic L-amino acid decarboxylase)
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