a tool for identifying drug-targetable redox-active disulphides

Mucin-like protocadherin

Intramolecular

Cysteine 30 and cysteine 98

A redox-regulated disulphide may form within Mucin-like protocadherin between cysteines 30 and 98 (5 and 73 respectively in this structure).

Details

Redox score ?

87

PDB code

Structure name

crystal structure of human mucin-like protocadherin ec1-2

Structure deposition date

2019-03-15

Thiol separation (Å)

2

Half-sphere exposure sum ?

61

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

30

Residue number B

98

Peptide name

Mucin-like protocadherin

Ligandability

Cysteine 30 of Mucin-like protocadherin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 98 of Mucin-like protocadherin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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