ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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LOC367586 protein

Intramolecular
Cysteine 41 and cysteine 115
Cysteine 163 and cysteine 218
A redox-regulated disulphide may form within LOC367586 protein between cysteines 41 and 115 (22 and 92 respectively in this structure).

Details

Redox score ?
80
PDB code
2g60
Structure name
structure of anti-flag m2 fab domain
Structure deposition date
2006-02-23
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q5BJZ2
Residue number A
41
Residue number B
115
Peptide name
LOC367586 protein

Ligandability

Cysteine 41 of LOC367586 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 115 of LOC367586 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within LOC367586 protein between cysteines 163 and 218 (142 and 208 respectively in this structure).

Details

Redox score ?
78
PDB code
2g60
Structure name
structure of anti-flag m2 fab domain
Structure deposition date
2006-02-23
Thiol separation (Å)
2
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q5BJZ2
Residue number A
163
Residue number B
218
Peptide name
LOC367586 protein

Ligandability

Cysteine 163 of LOC367586 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 218 of LOC367586 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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