Centromere protein W

Intermolecular

Cysteine 486 of Centromere protein T and cysteine 47

A redox-regulated disulphide may form between cysteine 486 of Centromere protein T and cysteine 47 of Centromere protein W. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7qoo

Structure name

structure of the human inner kinetochore ccan complex

Structure deposition date

2021-12-24

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Centromere protein T

Peptide B name

Centromere protein W

Peptide A accession

Q96BT3

Peptide B accession

Q5EE01

Peptide A residue number

486

Peptide B residue number

Ligandability

Cysteine 486 of Centromere protein T

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.