a tool for identifying drug-targetable redox-active disulphides

Torsin-1A-interacting protein 1

Intramolecular

Cysteine 424 and cysteine 582

A redox-regulated disulphide may form within Torsin-1A-interacting protein 1 between cysteines 424 and 582.

Details

Redox score ?

83

PDB code

Structure name

lap1(aa356-583), h

Structure deposition date

2014-06-27

Thiol separation (Å)

2

Half-sphere exposure sum ?

57

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

424

Residue number B

582

Peptide name

Torsin-1A-interacting protein 1

Ligandability

Cysteine 424 of Torsin-1A-interacting protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 582 of Torsin-1A-interacting protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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