a tool for identifying drug-targetable redox-active disulphides

Sterile alpha motif domain-containing protein 9

Intramolecular

Cysteine 283 and cysteine 316

A redox-regulated disulphide may form within Sterile alpha motif domain-containing protein 9 between cysteines 283 and 316.

Details

Redox score ?

77

PDB code

Structure name

crystal structure of hsamd9_dbd with dna

Structure deposition date

2020-11-23

Thiol separation (Å)

4

Half-sphere exposure sum ?

69

Minimum pK_a ?

8

% buried

86

Peptide accession

Residue number A

283

Residue number B

316

Peptide name

Sterile alpha motif domain-containing protein 9

Ligandability

Cysteine 283 of Sterile alpha motif domain-containing protein 9

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 316 of Sterile alpha motif domain-containing protein 9

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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