ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Collectin-12

Intramolecular
Cysteine 607 and cysteine 618
Cysteine 635 and cysteine 730
Cysteine 708 and cysteine 722
A redox-regulated disulphide may form within Collectin-12 between cysteines 607 and 618.

Details

Redox score ?
86
PDB code
2ox9
Structure name
mouse scavenger receptor c-type lectin carbohydrate-recognition domain
Structure deposition date
2007-02-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8K4Q8
Residue number A
607
Residue number B
618
Peptide name
Collectin-12

Ligandability

Cysteine 607 of Collectin-12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 618 of Collectin-12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Collectin-12 between cysteines 635 and 730.

Details

Redox score ?
82
PDB code
2ox9
Structure name
mouse scavenger receptor c-type lectin carbohydrate-recognition domain
Structure deposition date
2007-02-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8K4Q8
Residue number A
635
Residue number B
730
Peptide name
Collectin-12

Ligandability

Cysteine 635 of Collectin-12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 730 of Collectin-12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Collectin-12 between cysteines 708 and 722.

Details

Redox score ?
80
PDB code
2ox8
Structure name
human scavenger receptor c-type lectin carbohydrate- recognition domain
Structure deposition date
2007-02-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BYH7
Residue number A
708
Residue number B
722
Peptide name
Collectin-12

Ligandability

Cysteine 708 of Collectin-12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 722 of Collectin-12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: