Speedy protein A
Intramolecular
Cysteine 91 and cysteine 92
Cysteine 181 and cysteine 182
Cysteine 92 and cysteine 93
Cysteine 63 and cysteine 181
Cysteine 91 and cysteine 93
5uq1 D 91 D 92
A redox-regulated disulphide may form within Speedy protein A between cysteines 91 and 92.
Details
Redox score ?
73
PDB code
5uq1
Structure name
crystal structure of human cdk2-spy1 complex
Structure deposition date
2017-02-06
Thiol separation (Å)
5
Half-sphere exposure sum ?
35
Minimum pKa ?
9
% buried
0
Peptide accession
Q5MJ70
Residue number A
91
Residue number B
92
Peptide name
Speedy protein A
Ligandability
Cysteine 91 of Speedy protein A
Cysteine 92 of Speedy protein A
5uq3 B 181 B 182
A redox-regulated disulphide may form within Speedy protein A between cysteines 181 and 182. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
5uq3
Structure name
crystal structure of human cdk2-spy1-p27 ternary complex
Structure deposition date
2017-02-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
50
Minimum pKa ?
10
% buried
63
Peptide accession
Q5MJ70
Residue number A
181
Residue number B
182
Peptide name
Speedy protein A
Ligandability
Cysteine 181 of Speedy protein A
Cysteine 182 of Speedy protein A
7e34 B 92 B 93
A redox-regulated disulphide may form within Speedy protein A between cysteines 92 and 93. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
7e34
Structure name
crystal structure of sun1-speedy a-cdk2
Structure deposition date
2021-02-08
Thiol separation (Å)
8
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
24
Peptide accession
Q5MJ70
Residue number A
92
Residue number B
93
Peptide name
Speedy protein A
Ligandability
Cysteine 92 of Speedy protein A
Cysteine 93 of Speedy protein A
5uq1 D 63 D 181
A redox-regulated disulphide may form within Speedy protein A between cysteines 63 and 181. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
5uq1
Structure name
crystal structure of human cdk2-spy1 complex
Structure deposition date
2017-02-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
10
% buried
nan
Peptide accession
Q5MJ70
Residue number A
63
Residue number B
181
Peptide name
Speedy protein A
Ligandability
Cysteine 63 of Speedy protein A
Cysteine 181 of Speedy protein A
5uq3 B 91 B 93
A redox-regulated disulphide may form within Speedy protein A between cysteines 91 and 93. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
5uq3
Structure name
crystal structure of human cdk2-spy1-p27 ternary complex
Structure deposition date
2017-02-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
45
Minimum pKa ?
9
% buried
16
Peptide accession
Q5MJ70
Residue number A
91
Residue number B
93
Peptide name
Speedy protein A
Ligandability
Cysteine 91 of Speedy protein A
Cysteine 93 of Speedy protein A
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