a tool for identifying drug-targetable redox-active disulphides

V1-22 protein

Intramolecular

Cysteine 22 and cysteine 91

A redox-regulated disulphide may form within V1-22 protein between cysteines 22 and 91.

Details

Redox score ?

81

PDB code

Structure name

crystal structure of the recombinant variable domain 6jal2

Structure deposition date

2008-08-19

Thiol separation (Å)

2

Half-sphere exposure sum ?

93

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

22

Residue number B

91

Peptide name

V1-22 protein

Ligandability

Cysteine 22 of V1-22 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 91 of V1-22 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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