a tool for identifying drug-targetable redox-active disulphides

TRAV14-3

Intramolecular

Cysteine 50 and cysteine 117

A redox-regulated disulphide may form within TRAV14-3 between cysteines 50 and 117 (22 and 90 respectively in this structure).

Details

Redox score ?

80

PDB code

Structure name

crystal structure of mouse tcr 172

Structure deposition date

2004-07-21

Thiol separation (Å)

2

Half-sphere exposure sum ?

84

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

50

Residue number B

117

Peptide name

TRAV14-3

Ligandability

Cysteine 50 of TRAV14-3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 117 of TRAV14-3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: