a tool for identifying drug-targetable redox-active disulphides

TRADV16D

Intramolecular

Cysteine 44 and cysteine 113

A redox-regulated disulphide may form within TRADV16D between cysteines 44 and 113 (22 and 90 respectively in this structure).

Details

Redox score ?

81

PDB code

Structure name

crystal structure of bm3

Structure deposition date

2007-01-18

Thiol separation (Å)

2

Half-sphere exposure sum ?

83

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

44

Residue number B

113

Peptide name

TRADV16D

Ligandability

Cysteine 44 of TRADV16D

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 113 of TRADV16D

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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