a tool for identifying drug-targetable redox-active disulphides

Interleukin-3

Intramolecular

Cysteine 43 and cysteine 106

A redox-regulated disulphide may form within Interleukin-3 between cysteines 43 and 106.

Details

Redox score ?

86

PDB code

Structure name

solution structure of murine interleukin 3

Structure deposition date

2010-09-20

Thiol separation (Å)

2

Half-sphere exposure sum ?

52

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

43

Residue number B

106

Peptide name

Interleukin-3

Ligandability

Cysteine 43 of Interleukin-3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 106 of Interleukin-3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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