ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Queuosine salvage protein

Intramolecular
Cysteine 281 and cysteine 285
A redox-regulated disulphide may form within Queuosine salvage protein between cysteines 281 and 285. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
32
PDB code
7ugk
Structure name
crystal structure of the human queuine salvage enzyme duf2419, wild- type apo form
Structure deposition date
2022-03-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
96
Minimum pKa ?
12
% buried
93
Peptide accession
Q5T6V5
Residue number A
281
Residue number B
285
Peptide name
Queuosine salvage protein

Ligandability

Cysteine 281 of Queuosine salvage protein

Cysteine 285 of Queuosine salvage protein

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