Roquin-1
Intramolecular
Cysteine 14 and cysteine 17
Cysteine 14 and cysteine 38
Cysteine 17 and cysteine 38
Cysteine 33 and cysteine 50
Cysteine 14 and cysteine 41
Cysteine 38 and cysteine 41
Cysteine 17 and cysteine 41
Cysteine 14 and cysteine 50
Cysteine 41 and cysteine 50
4txa A 14 A 17
A redox-regulated disulphide may form within Roquin-1 between cysteines 14 and 17.
Details
Redox score ?
82
PDB code
4txa
Structure name
crystal structure of n-terminus of roquin
Structure deposition date
2014-07-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
7
% buried
26
Peptide accession
Q4VGL6
Residue number A
14
Residue number B
17
Peptide name
Roquin-1
Ligandability
Cysteine 14 of Roquin-1
Cysteine 17 of Roquin-1
4txa A 14 A 38
A redox-regulated disulphide may form within Roquin-1 between cysteines 14 and 38.
Details
Redox score ?
80
PDB code
4txa
Structure name
crystal structure of n-terminus of roquin
Structure deposition date
2014-07-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
7
% buried
35
Peptide accession
Q4VGL6
Residue number A
14
Residue number B
38
Peptide name
Roquin-1
Ligandability
Cysteine 14 of Roquin-1
Cysteine 38 of Roquin-1
4txa A 17 A 38
A redox-regulated disulphide may form within Roquin-1 between cysteines 17 and 38.
Details
Redox score ?
80
PDB code
4txa
Structure name
crystal structure of n-terminus of roquin
Structure deposition date
2014-07-03
Thiol separation (Å)
3
Half-sphere exposure sum ?
59
Minimum pKa ?
8
% buried
18
Peptide accession
Q4VGL6
Residue number A
17
Residue number B
38
Peptide name
Roquin-1
Ligandability
Cysteine 17 of Roquin-1
Cysteine 38 of Roquin-1
4txa A 33 A 50
A redox-regulated disulphide may form within Roquin-1 between cysteines 33 and 50.
Details
Redox score ?
74
PDB code
4txa
Structure name
crystal structure of n-terminus of roquin
Structure deposition date
2014-07-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
8
% buried
34
Peptide accession
Q4VGL6
Residue number A
33
Residue number B
50
Peptide name
Roquin-1
Ligandability
Cysteine 33 of Roquin-1
Cysteine 50 of Roquin-1
4txa A 14 A 41
A redox-regulated disulphide may form within Roquin-1 between cysteines 14 and 41.
Details
Redox score ?
73
PDB code
4txa
Structure name
crystal structure of n-terminus of roquin
Structure deposition date
2014-07-03
Thiol separation (Å)
5
Half-sphere exposure sum ?
58
Minimum pKa ?
7
% buried
29
Peptide accession
Q4VGL6
Residue number A
14
Residue number B
41
Peptide name
Roquin-1
Ligandability
Cysteine 14 of Roquin-1
Cysteine 41 of Roquin-1
4txa A 38 A 41
A redox-regulated disulphide may form within Roquin-1 between cysteines 38 and 41.
Details
Redox score ?
66
PDB code
4txa
Structure name
crystal structure of n-terminus of roquin
Structure deposition date
2014-07-03
Thiol separation (Å)
5
Half-sphere exposure sum ?
65
Minimum pKa ?
9
% buried
21
Peptide accession
Q4VGL6
Residue number A
38
Residue number B
41
Peptide name
Roquin-1
Ligandability
Cysteine 38 of Roquin-1
Cysteine 41 of Roquin-1
4txa A 17 A 41
A redox-regulated disulphide may form within Roquin-1 between cysteines 17 and 41.
Details
Redox score ?
64
PDB code
4txa
Structure name
crystal structure of n-terminus of roquin
Structure deposition date
2014-07-03
Thiol separation (Å)
6
Half-sphere exposure sum ?
48
Minimum pKa ?
8
% buried
12
Peptide accession
Q4VGL6
Residue number A
17
Residue number B
41
Peptide name
Roquin-1
Ligandability
Cysteine 17 of Roquin-1
Cysteine 41 of Roquin-1
4txa A 14 A 50
A redox-regulated disulphide may form within Roquin-1 between cysteines 14 and 50. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
4txa
Structure name
crystal structure of n-terminus of roquin
Structure deposition date
2014-07-03
Thiol separation (Å)
10
Half-sphere exposure sum ?
57
Minimum pKa ?
7
% buried
34
Peptide accession
Q4VGL6
Residue number A
14
Residue number B
50
Peptide name
Roquin-1
Ligandability
Cysteine 14 of Roquin-1
Cysteine 50 of Roquin-1
4txa A 41 A 50
A redox-regulated disulphide may form within Roquin-1 between cysteines 41 and 50. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
4txa
Structure name
crystal structure of n-terminus of roquin
Structure deposition date
2014-07-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
53
Minimum pKa ?
8
% buried
20
Peptide accession
Q4VGL6
Residue number A
41
Residue number B
50
Peptide name
Roquin-1
Ligandability
Cysteine 41 of Roquin-1
Cysteine 50 of Roquin-1
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