ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Signal-regulatory protein beta-1 isoform 3

Intramolecular
Cysteine 54 and cysteine 120
A redox-regulated disulphide may form within Signal-regulatory protein beta-1 isoform 3 between cysteines 54 and 120 (25 and 91 respectively in this structure).

Details

Redox score ?
81
PDB code
2jjv
Structure name
structure of human signal regulatory protein (sirp) beta(2)
Structure deposition date
2008-04-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q5TFQ8
Residue number A
54
Residue number B
120
Peptide name
Signal-regulatory protein beta-1 isoform 3

Ligandability

Cysteine 54 of Signal-regulatory protein beta-1 isoform 3

Cysteine 120 of Signal-regulatory protein beta-1 isoform 3

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