Zinc finger MYND-type containing 8
Intramolecular
Cysteine 102 and cysteine 105
Cysteine 66 and cysteine 69
Cysteine 66 and cysteine 89
Cysteine 78 and cysteine 102
Cysteine 69 and cysteine 89
Cysteine 81 and cysteine 102
Cysteine 81 and cysteine 105
Cysteine 78 and cysteine 81
Cysteine 78 and cysteine 105
Cysteine 77 and cysteine 78
More...Cysteine 77 and cysteine 102
Cysteine 77 and cysteine 81
7cwh B 147 B 150
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 102 and 105 (147 and 150 respectively in this structure).
Details
Redox score ?
87
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
3
Half-sphere exposure sum ?
52
Minimum pKa ?
7
% buried
10
Peptide accession
Q5TH12
Residue number A
102
Residue number B
105
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 102 of Zinc finger MYND-type containing 8
Cysteine 105 of Zinc finger MYND-type containing 8
7cwh B 111 B 114
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 66 and 69 (111 and 114 respectively in this structure).
Details
Redox score ?
85
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
7
% buried
2
Peptide accession
Q5TH12
Residue number A
66
Residue number B
69
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 66 of Zinc finger MYND-type containing 8
Cysteine 69 of Zinc finger MYND-type containing 8
7cwh B 111 B 134
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 66 and 89 (111 and 134 respectively in this structure).
Details
Redox score ?
83
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
7
% buried
2
Peptide accession
Q5TH12
Residue number A
66
Residue number B
89
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 66 of Zinc finger MYND-type containing 8
Cysteine 89 of Zinc finger MYND-type containing 8
7cwh B 123 B 147
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 78 and 102 (123 and 147 respectively in this structure).
Details
Redox score ?
83
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
7
% buried
19
Peptide accession
Q5TH12
Residue number A
78
Residue number B
102
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 78 of Zinc finger MYND-type containing 8
Cysteine 102 of Zinc finger MYND-type containing 8
7cwh B 114 B 134
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 69 and 89 (114 and 134 respectively in this structure).
Details
Redox score ?
83
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
3
Half-sphere exposure sum ?
40
Minimum pKa ?
9
% buried
0
Peptide accession
Q5TH12
Residue number A
69
Residue number B
89
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 69 of Zinc finger MYND-type containing 8
Cysteine 89 of Zinc finger MYND-type containing 8
7cwh B 126 B 147
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 81 and 102 (126 and 147 respectively in this structure).
Details
Redox score ?
82
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
7
% buried
9
Peptide accession
Q5TH12
Residue number A
81
Residue number B
102
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 81 of Zinc finger MYND-type containing 8
Cysteine 102 of Zinc finger MYND-type containing 8
7cwh B 126 B 150
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 81 and 105 (126 and 150 respectively in this structure).
Details
Redox score ?
81
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
39
Minimum pKa ?
10
% buried
2
Peptide accession
Q5TH12
Residue number A
81
Residue number B
105
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 81 of Zinc finger MYND-type containing 8
Cysteine 105 of Zinc finger MYND-type containing 8
7cwh B 123 B 126
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 78 and 81 (123 and 126 respectively in this structure).
Details
Redox score ?
79
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
11
Peptide accession
Q5TH12
Residue number A
78
Residue number B
81
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 78 of Zinc finger MYND-type containing 8
Cysteine 81 of Zinc finger MYND-type containing 8
7cwh B 123 B 150
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 78 and 105 (123 and 150 respectively in this structure).
Details
Redox score ?
77
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
12
Peptide accession
Q5TH12
Residue number A
78
Residue number B
105
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 78 of Zinc finger MYND-type containing 8
Cysteine 105 of Zinc finger MYND-type containing 8
7cwh B 122 B 123
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 77 and 78 (122 and 123 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
7
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
21
Peptide accession
Q5TH12
Residue number A
77
Residue number B
78
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 77 of Zinc finger MYND-type containing 8
Cysteine 78 of Zinc finger MYND-type containing 8
7cwh B 122 B 147
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 77 and 102 (122 and 147 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
7
% buried
19
Peptide accession
Q5TH12
Residue number A
77
Residue number B
102
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 77 of Zinc finger MYND-type containing 8
Cysteine 102 of Zinc finger MYND-type containing 8
7cwh B 122 B 126
A redox-regulated disulphide may form within Zinc finger MYND-type containing 8 between cysteines 77 and 81 (122 and 126 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7cwh
Structure name
structural basis of rack7 phd to read a pediatric glioblastoma- associated histone mutation h3
Structure deposition date
2020-08-28
Thiol separation (Å)
9
Half-sphere exposure sum ?
51
Minimum pKa ?
10
% buried
11
Peptide accession
Q5TH12
Residue number A
77
Residue number B
81
Peptide name
Zinc finger MYND-type containing 8
Ligandability
Cysteine 77 of Zinc finger MYND-type containing 8
Cysteine 81 of Zinc finger MYND-type containing 8
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