ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Rootletin

Intermolecular
Cysteine 1152 and cysteine 1152
A redox-regulated disulphide may form between two units of Rootletin at cysteines 1152 and 1152.

Details

Redox score ?
80
PDB code
6l5j
Structure name
crystal structure of human rootletin 1108-1317
Structure deposition date
2019-10-23
Thiol separation (Å)
5
Half-sphere exposure sum ?
nan
Minimum pKa ?
10
% buried
2
Peptide A name
Rootletin
Peptide B name
Rootletin
Peptide A accession
Q5TZA2
Peptide B accession
Q5TZA2
Peptide A residue number
1152
Peptide B residue number
1152

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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