N-terminal Xaa-Pro-Lys N-methyltransferase 2

Intramolecular

A redox-regulated disulphide may form within N-terminal Xaa-Pro-Lys N-methyltransferase 2 between cysteines 123 and 208. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6kds

Structure name

crystal structure of human nrmt2 in complex with alpha-n- monomethylated human cenp-a peptide

Structure deposition date

2019-07-02

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

Q5VVY1

Residue number A

123

Residue number B

208

Peptide name

N-terminal Xaa-Pro-Lys N-methyltransferase 2

Ligandability

Cysteine 123 of N-terminal Xaa-Pro-Lys N-methyltransferase 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.