ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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UL16-binding protein 6

Intramolecular
Cysteine 50 and cysteine 66
Cysteine 127 and cysteine 190
A redox-regulated disulphide may form within UL16-binding protein 6 between cysteines 50 and 66.

Details

Redox score ?
84
PDB code
4s0u
Structure name
crystal structure of nkg2d in complex with ulbp6
Structure deposition date
2015-01-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q5VY80
Residue number A
50
Residue number B
66
Peptide name
UL16-binding protein 6

Ligandability

Cysteine 50 of UL16-binding protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 66 of UL16-binding protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within UL16-binding protein 6 between cysteines 127 and 190.

Details

Redox score ?
80
PDB code
4s0u
Structure name
crystal structure of nkg2d in complex with ulbp6
Structure deposition date
2015-01-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q5VY80
Residue number A
127
Residue number B
190
Peptide name
UL16-binding protein 6

Ligandability

Cysteine 127 of UL16-binding protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 190 of UL16-binding protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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