Terminal uridylyltransferase 7
Intramolecular
Cysteine 1347 and cysteine 1360
Cysteine 1347 and cysteine 1350
Cysteine 1350 and cysteine 1360
Cysteine 1346 and cysteine 1350
Cysteine 1346 and cysteine 1347
Cysteine 1005 and cysteine 1008
Cysteine 1062 and cysteine 1076
5w0n A 1347 A 1360
A redox-regulated disulphide may form within Terminal uridylyltransferase 7 between cysteines 1347 and 1360.
Details
Redox score ?
87
PDB code
5w0n
Structure name
structure of human tut7 catalytic module (cm) in complex with umpnpp and u2 rna
Structure deposition date
2017-05-31
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
6
% buried
31
Peptide accession
Q5VYS8
Residue number A
1347
Residue number B
1360
Peptide name
Terminal uridylyltransferase 7
Ligandability
Cysteine 1347 of Terminal uridylyltransferase 7
Cysteine 1360 of Terminal uridylyltransferase 7
5w0m C 1347 C 1350
A redox-regulated disulphide may form within Terminal uridylyltransferase 7 between cysteines 1347 and 1350.
Details
Redox score ?
84
PDB code
5w0m
Structure name
structure of human tut7 catalytic module (cm) in complex with u5 rna
Structure deposition date
2017-05-31
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
5
% buried
16
Peptide accession
Q5VYS8
Residue number A
1347
Residue number B
1350
Peptide name
Terminal uridylyltransferase 7
Ligandability
Cysteine 1347 of Terminal uridylyltransferase 7
Cysteine 1350 of Terminal uridylyltransferase 7
5w0m A 1350 A 1360
A redox-regulated disulphide may form within Terminal uridylyltransferase 7 between cysteines 1350 and 1360.
Details
Redox score ?
75
PDB code
5w0m
Structure name
structure of human tut7 catalytic module (cm) in complex with u5 rna
Structure deposition date
2017-05-31
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
9
% buried
51
Peptide accession
Q5VYS8
Residue number A
1350
Residue number B
1360
Peptide name
Terminal uridylyltransferase 7
Ligandability
Cysteine 1350 of Terminal uridylyltransferase 7
Cysteine 1360 of Terminal uridylyltransferase 7
5w0b A 1346 A 1350
A redox-regulated disulphide may form within Terminal uridylyltransferase 7 between cysteines 1346 and 1350. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
5w0b
Structure name
structure of human tut7 catalytic module (cm)
Structure deposition date
2017-05-30
Thiol separation (Å)
7
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
33
Peptide accession
Q5VYS8
Residue number A
1346
Residue number B
1350
Peptide name
Terminal uridylyltransferase 7
Ligandability
Cysteine 1346 of Terminal uridylyltransferase 7
Cysteine 1350 of Terminal uridylyltransferase 7
5w0b A 1346 A 1347
A redox-regulated disulphide may form within Terminal uridylyltransferase 7 between cysteines 1346 and 1347. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
5w0b
Structure name
structure of human tut7 catalytic module (cm)
Structure deposition date
2017-05-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
52
Minimum pKa ?
7
% buried
20
Peptide accession
Q5VYS8
Residue number A
1346
Residue number B
1347
Peptide name
Terminal uridylyltransferase 7
Ligandability
Cysteine 1346 of Terminal uridylyltransferase 7
Cysteine 1347 of Terminal uridylyltransferase 7
5w0m B 1005 B 1008
A redox-regulated disulphide may form within Terminal uridylyltransferase 7 between cysteines 1005 and 1008. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
5w0m
Structure name
structure of human tut7 catalytic module (cm) in complex with u5 rna
Structure deposition date
2017-05-31
Thiol separation (Å)
6
Half-sphere exposure sum ?
78
Minimum pKa ?
12
% buried
100
Peptide accession
Q5VYS8
Residue number A
1005
Residue number B
1008
Peptide name
Terminal uridylyltransferase 7
Ligandability
Cysteine 1005 of Terminal uridylyltransferase 7
Cysteine 1008 of Terminal uridylyltransferase 7
5w0b B 1062 B 1076
A redox-regulated disulphide may form within Terminal uridylyltransferase 7 between cysteines 1062 and 1076. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
5w0b
Structure name
structure of human tut7 catalytic module (cm)
Structure deposition date
2017-05-30
Thiol separation (Å)
10
Half-sphere exposure sum ?
66
Minimum pKa ?
10
% buried
48
Peptide accession
Q5VYS8
Residue number A
1062
Residue number B
1076
Peptide name
Terminal uridylyltransferase 7
Ligandability
Cysteine 1062 of Terminal uridylyltransferase 7
Cysteine 1076 of Terminal uridylyltransferase 7
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