Muscleblind-like protein 2
Intramolecular
Cysteine 226 and cysteine 231
Cysteine 218 and cysteine 231
Cysteine 190 and cysteine 197
Cysteine 19 and cysteine 27
Cysteine 53 and cysteine 66
Cysteine 27 and cysteine 34
Cysteine 182 and cysteine 190
Cysteine 53 and cysteine 61
Cysteine 19 and cysteine 34
Cysteine 61 and cysteine 66
More...Cysteine 182 and cysteine 197
Cysteine 218 and cysteine 226
Cysteine 43 and cysteine 66
Cysteine 43 and cysteine 53
Cysteine 43 and cysteine 61
2e5s A 67 A 72
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 226 and 231 (67 and 72 respectively in this structure).
Details
Redox score ?
90
PDB code
2e5s
Structure name
solution structure of the zf-ccchx2 domain of muscleblind-like 2, isoform 1 [homo sapiens]
Structure deposition date
2006-12-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
34
Minimum pKa ?
7
% buried
0
Peptide accession
Q5VZF2
Residue number A
226
Residue number B
231
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 226 of Muscleblind-like protein 2
Cysteine 231 of Muscleblind-like protein 2
2e5s A 59 A 72
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 218 and 231 (59 and 72 respectively in this structure).
Details
Redox score ?
87
PDB code
2e5s
Structure name
solution structure of the zf-ccchx2 domain of muscleblind-like 2, isoform 1 [homo sapiens]
Structure deposition date
2006-12-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
7
% buried
2
Peptide accession
Q5VZF2
Residue number A
218
Residue number B
231
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 218 of Muscleblind-like protein 2
Cysteine 231 of Muscleblind-like protein 2
2e5s A 31 A 38
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 190 and 197 (31 and 38 respectively in this structure).
Details
Redox score ?
86
PDB code
2e5s
Structure name
solution structure of the zf-ccchx2 domain of muscleblind-like 2, isoform 1 [homo sapiens]
Structure deposition date
2006-12-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
8
% buried
0
Peptide accession
Q5VZF2
Residue number A
190
Residue number B
197
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 190 of Muscleblind-like protein 2
Cysteine 197 of Muscleblind-like protein 2
2rpp A 26 A 34
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 19 and 27 (26 and 34 respectively in this structure).
Details
Redox score ?
86
PDB code
2rpp
Structure name
solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2
Structure deposition date
2008-06-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
8
% buried
0
Peptide accession
Q5VZF2
Residue number A
19
Residue number B
27
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 19 of Muscleblind-like protein 2
Cysteine 27 of Muscleblind-like protein 2
2rpp A 60 A 73
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 53 and 66 (60 and 73 respectively in this structure).
Details
Redox score ?
86
PDB code
2rpp
Structure name
solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2
Structure deposition date
2008-06-24
Thiol separation (Å)
3
Half-sphere exposure sum ?
55
Minimum pKa ?
7
% buried
11
Peptide accession
Q5VZF2
Residue number A
53
Residue number B
66
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 53 of Muscleblind-like protein 2
Cysteine 66 of Muscleblind-like protein 2
2rpp A 34 A 41
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 27 and 34 (34 and 41 respectively in this structure).
Details
Redox score ?
85
PDB code
2rpp
Structure name
solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2
Structure deposition date
2008-06-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
8
% buried
0
Peptide accession
Q5VZF2
Residue number A
27
Residue number B
34
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 27 of Muscleblind-like protein 2
Cysteine 34 of Muscleblind-like protein 2
2e5s A 23 A 31
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 182 and 190 (23 and 31 respectively in this structure).
Details
Redox score ?
85
PDB code
2e5s
Structure name
solution structure of the zf-ccchx2 domain of muscleblind-like 2, isoform 1 [homo sapiens]
Structure deposition date
2006-12-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
8
% buried
0
Peptide accession
Q5VZF2
Residue number A
182
Residue number B
190
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 182 of Muscleblind-like protein 2
Cysteine 190 of Muscleblind-like protein 2
2rpp A 60 A 68
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 53 and 61 (60 and 68 respectively in this structure).
Details
Redox score ?
85
PDB code
2rpp
Structure name
solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2
Structure deposition date
2008-06-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
7
% buried
9
Peptide accession
Q5VZF2
Residue number A
53
Residue number B
61
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 53 of Muscleblind-like protein 2
Cysteine 61 of Muscleblind-like protein 2
2rpp A 26 A 41
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 19 and 34 (26 and 41 respectively in this structure).
Details
Redox score ?
84
PDB code
2rpp
Structure name
solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2
Structure deposition date
2008-06-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
8
% buried
0
Peptide accession
Q5VZF2
Residue number A
19
Residue number B
34
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 19 of Muscleblind-like protein 2
Cysteine 34 of Muscleblind-like protein 2
2rpp A 68 A 73
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 61 and 66 (68 and 73 respectively in this structure).
Details
Redox score ?
83
PDB code
2rpp
Structure name
solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2
Structure deposition date
2008-06-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
9
% buried
2
Peptide accession
Q5VZF2
Residue number A
61
Residue number B
66
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 61 of Muscleblind-like protein 2
Cysteine 66 of Muscleblind-like protein 2
2e5s A 23 A 38
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 182 and 197 (23 and 38 respectively in this structure).
Details
Redox score ?
82
PDB code
2e5s
Structure name
solution structure of the zf-ccchx2 domain of muscleblind-like 2, isoform 1 [homo sapiens]
Structure deposition date
2006-12-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
8
% buried
1
Peptide accession
Q5VZF2
Residue number A
182
Residue number B
197
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 182 of Muscleblind-like protein 2
Cysteine 197 of Muscleblind-like protein 2
2e5s A 59 A 67
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 218 and 226 (59 and 67 respectively in this structure).
Details
Redox score ?
82
PDB code
2e5s
Structure name
solution structure of the zf-ccchx2 domain of muscleblind-like 2, isoform 1 [homo sapiens]
Structure deposition date
2006-12-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
9
% buried
2
Peptide accession
Q5VZF2
Residue number A
218
Residue number B
226
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 218 of Muscleblind-like protein 2
Cysteine 226 of Muscleblind-like protein 2
2rpp A 50 A 73
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 43 and 66 (50 and 73 respectively in this structure).
Details
Redox score ?
72
PDB code
2rpp
Structure name
solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2
Structure deposition date
2008-06-24
Thiol separation (Å)
6
Half-sphere exposure sum ?
44
Minimum pKa ?
9
% buried
12
Peptide accession
Q5VZF2
Residue number A
43
Residue number B
66
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 43 of Muscleblind-like protein 2
Cysteine 66 of Muscleblind-like protein 2
2rpp A 50 A 60
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 43 and 53 (50 and 60 respectively in this structure).
Details
Redox score ?
60
PDB code
2rpp
Structure name
solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2
Structure deposition date
2008-06-24
Thiol separation (Å)
8
Half-sphere exposure sum ?
55
Minimum pKa ?
7
% buried
18
Peptide accession
Q5VZF2
Residue number A
43
Residue number B
53
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 43 of Muscleblind-like protein 2
Cysteine 53 of Muscleblind-like protein 2
2rpp A 50 A 68
A redox-regulated disulphide may form within Muscleblind-like protein 2 between cysteines 43 and 61 (50 and 68 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
2rpp
Structure name
solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2
Structure deposition date
2008-06-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
40
Minimum pKa ?
10
% buried
10
Peptide accession
Q5VZF2
Residue number A
43
Residue number B
61
Peptide name
Muscleblind-like protein 2
Ligandability
Cysteine 43 of Muscleblind-like protein 2
Cysteine 61 of Muscleblind-like protein 2
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