ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

SPRY domain-containing protein 7

Intramolecular
Cysteine 54 and cysteine 173
A redox-regulated disulphide may form within SPRY domain-containing protein 7 between cysteines 54 and 173. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
31
PDB code
7ccb
Structure name
crystal structure of the spry domain-containing protein 7 (spry7)
Structure deposition date
2020-06-16
Thiol separation (Å)
9
Half-sphere exposure sum ?
96
Minimum pKa ?
12
% buried
90
Peptide accession
Q5W111
Residue number A
54
Residue number B
173
Peptide name
SPRY domain-containing protein 7

Ligandability

Cysteine 54 of SPRY domain-containing protein 7

Cysteine 173 of SPRY domain-containing protein 7

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