F-box only protein 31
Intramolecular
Cysteine 463 and cysteine 466
Cysteine 206 and cysteine 230
Cysteine 111 and cysteine 131
Cysteine 230 and cysteine 283
Cysteine 206 and cysteine 283
Cysteine 118 and cysteine 131
Cysteine 111 and cysteine 118
5vzu B 463 B 466
A redox-regulated disulphide may form within F-box only protein 31 between cysteines 463 and 466.
Details
Redox score ?
76
PDB code
5vzu
Structure name
crystal structure of the skp1-fbxo31-cyclin d1 complex
Structure deposition date
2017-05-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
7
% buried
70
Peptide accession
Q5XUX0
Residue number A
463
Residue number B
466
Peptide name
F-box only protein 31
Ligandability
Cysteine 463 of F-box only protein 31
Cysteine 466 of F-box only protein 31
5vzt B 206 B 230
A redox-regulated disulphide may form within F-box only protein 31 between cysteines 206 and 230.
Details
Redox score ?
75
PDB code
5vzt
Structure name
crystal structure of the skp1-fbxo31 complex
Structure deposition date
2017-05-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
70
Minimum pKa ?
9
% buried
47
Peptide accession
Q5XUX0
Residue number A
206
Residue number B
230
Peptide name
F-box only protein 31
Ligandability
Cysteine 206 of F-box only protein 31
Cysteine 230 of F-box only protein 31
5vzt B 111 B 131
A redox-regulated disulphide may form within F-box only protein 31 between cysteines 111 and 131.
Details
Redox score ?
66
PDB code
5vzt
Structure name
crystal structure of the skp1-fbxo31 complex
Structure deposition date
2017-05-29
Thiol separation (Å)
5
Half-sphere exposure sum ?
77
Minimum pKa ?
8
% buried
70
Peptide accession
Q5XUX0
Residue number A
111
Residue number B
131
Peptide name
F-box only protein 31
Ligandability
Cysteine 111 of F-box only protein 31
Cysteine 131 of F-box only protein 31
5vzu D 230 D 283
A redox-regulated disulphide may form within F-box only protein 31 between cysteines 230 and 283.
Details
Redox score ?
64
PDB code
5vzu
Structure name
crystal structure of the skp1-fbxo31-cyclin d1 complex
Structure deposition date
2017-05-29
Thiol separation (Å)
6
Half-sphere exposure sum ?
59
Minimum pKa ?
8
% buried
31
Peptide accession
Q5XUX0
Residue number A
230
Residue number B
283
Peptide name
F-box only protein 31
Ligandability
Cysteine 230 of F-box only protein 31
Cysteine 283 of F-box only protein 31
5vzt B 206 B 283
A redox-regulated disulphide may form within F-box only protein 31 between cysteines 206 and 283. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
5vzt
Structure name
crystal structure of the skp1-fbxo31 complex
Structure deposition date
2017-05-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
68
Minimum pKa ?
9
% buried
46
Peptide accession
Q5XUX0
Residue number A
206
Residue number B
283
Peptide name
F-box only protein 31
Ligandability
Cysteine 206 of F-box only protein 31
Cysteine 283 of F-box only protein 31
5vzt B 118 B 131
A redox-regulated disulphide may form within F-box only protein 31 between cysteines 118 and 131. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
5vzt
Structure name
crystal structure of the skp1-fbxo31 complex
Structure deposition date
2017-05-29
Thiol separation (Å)
8
Half-sphere exposure sum ?
63
Minimum pKa ?
8
% buried
28
Peptide accession
Q5XUX0
Residue number A
118
Residue number B
131
Peptide name
F-box only protein 31
Ligandability
Cysteine 118 of F-box only protein 31
Cysteine 131 of F-box only protein 31
5vzu D 111 D 118
A redox-regulated disulphide may form within F-box only protein 31 between cysteines 111 and 118. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
5vzu
Structure name
crystal structure of the skp1-fbxo31-cyclin d1 complex
Structure deposition date
2017-05-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
9
% buried
42
Peptide accession
Q5XUX0
Residue number A
111
Residue number B
118
Peptide name
F-box only protein 31
Ligandability
Cysteine 111 of F-box only protein 31
Cysteine 118 of F-box only protein 31
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