a tool for identifying drug-targetable redox-active disulphides

Biliary glycoprotein

Intramolecular

Cysteine 166 and cysteine 214

A redox-regulated disulphide may form within Biliary glycoprotein between cysteines 166 and 214 (132 and 180 respectively in this structure).

Details

Redox score ?

81

PDB code

Structure name

crystal structure of murine ceacam1b

Structure deposition date

2017-05-12

Thiol separation (Å)

2

Half-sphere exposure sum ?

80

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

166

Residue number B

214

Peptide name

Biliary glycoprotein

Ligandability

Cysteine 166 of Biliary glycoprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 214 of Biliary glycoprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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