ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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BTB/POZ domain-containing protein KCTD16

Intermolecular
Cysteine 250 and cysteine 250
A redox-regulated disulphide may form between two units of BTB/POZ domain-containing protein KCTD16 at cysteines 250 and 250. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
6qb7
Structure name
structure of the h1 domain of human kctd16
Structure deposition date
2018-12-20
Thiol separation (Å)
6
Half-sphere exposure sum ?
86
Minimum pKa ?
12
% buried
100
Peptide A name
BTB/POZ domain-containing protein KCTD16
Peptide B name
BTB/POZ domain-containing protein KCTD16
Peptide A accession
Q68DU8
Peptide B accession
Q68DU8
Peptide A residue number
250
Peptide B residue number
250

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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