a tool for identifying drug-targetable redox-active disulphides

MKIAA0668 protein

Intramolecular

Cysteine 578 and cysteine 682

A redox-regulated disulphide may form within MKIAA0668 protein between cysteines 578 and 682 (583 and 687 respectively in this structure).

Details

Redox score ?

68

PDB code

Structure name

crystal structure of cc2-sun of mouse sun2

Structure deposition date

2015-10-21

Thiol separation (Å)

4

Half-sphere exposure sum ?

93

Minimum pK_a ?

7

% buried

100

Peptide accession

Residue number A

578

Residue number B

682

Peptide name

MKIAA0668 protein

Ligandability

Cysteine 578 of MKIAA0668 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 682 of MKIAA0668 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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