a tool for identifying drug-targetable redox-active disulphides

U11/U12 small nuclear ribonucleoprotein 48 kDa protein

Intramolecular

Cysteine 58 and cysteine 78

A redox-regulated disulphide may form within U11/U12 small nuclear ribonucleoprotein 48 kDa protein between cysteines 58 and 78.

Details

Redox score ?

86

PDB code

Structure name

u11-48k chhc zn-finger protein domain

Structure deposition date

2008-07-18

Thiol separation (Å)

4

Half-sphere exposure sum ?

49

Minimum pK_a ?

7

% buried

0

Peptide accession

Residue number A

58

Residue number B

78

Peptide name

U11/U12 small nuclear ribonucleoprotein 48 kDa protein

Ligandability

Cysteine 58 of U11/U12 small nuclear ribonucleoprotein 48 kDa protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 78 of U11/U12 small nuclear ribonucleoprotein 48 kDa protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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