ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Fanconi anemia core complex-associated protein 20

Intramolecular
Cysteine 147 and cysteine 150
Cysteine 150 and cysteine 170
Cysteine 147 and cysteine 170
A redox-regulated disulphide may form within Fanconi anemia core complex-associated protein 20 between cysteines 147 and 150.

Details

Redox score ?
84
PDB code
3wwq
Structure name
crystal structure of faap20 ubz domain in complex with lys63-linked diubiquitin
Structure deposition date
2014-06-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
7
% buried
13
Peptide accession
Q6NZ36
Residue number A
147
Residue number B
150
Peptide name
Fanconi anemia core complex-associated protein 20

Ligandability

Cysteine 147 of Fanconi anemia core complex-associated protein 20

Cysteine 150 of Fanconi anemia core complex-associated protein 20

A redox-regulated disulphide may form within Fanconi anemia core complex-associated protein 20 between cysteines 150 and 170.

Details

Redox score ?
80
PDB code
3wwq
Structure name
crystal structure of faap20 ubz domain in complex with lys63-linked diubiquitin
Structure deposition date
2014-06-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
7
% buried
10
Peptide accession
Q6NZ36
Residue number A
150
Residue number B
170
Peptide name
Fanconi anemia core complex-associated protein 20

Ligandability

Cysteine 150 of Fanconi anemia core complex-associated protein 20

Cysteine 170 of Fanconi anemia core complex-associated protein 20

A redox-regulated disulphide may form within Fanconi anemia core complex-associated protein 20 between cysteines 147 and 170.

Details

Redox score ?
77
PDB code
3wwq
Structure name
crystal structure of faap20 ubz domain in complex with lys63-linked diubiquitin
Structure deposition date
2014-06-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
8
% buried
21
Peptide accession
Q6NZ36
Residue number A
147
Residue number B
170
Peptide name
Fanconi anemia core complex-associated protein 20

Ligandability

Cysteine 147 of Fanconi anemia core complex-associated protein 20

Cysteine 170 of Fanconi anemia core complex-associated protein 20

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