Zinc finger CCHC domain-containing protein 8
Intermolecular
Cysteine 56 and cysteine 56
Intramolecular
Cysteine 229 and cysteine 242
Cysteine 229 and cysteine 232
Cysteine 232 and cysteine 242
7s7b B 56 F 56
A redox-regulated disulphide may form between two units of Zinc finger CCHC domain-containing protein 8 at cysteines 56 and 56.
Details
Redox score ?
69
PDB code
7s7b
Structure name
human nuclear exosome targeting (next) complex homodimer bound to rna (substrate 1)
Structure deposition date
2021-09-15
Thiol separation (Å)
5
Half-sphere exposure sum ?
50
Minimum pKa ?
10
% buried
10
Peptide A name
Zinc finger CCHC domain-containing protein 8
Peptide B name
Zinc finger CCHC domain-containing protein 8
Peptide A accession
Q6NZY4
Peptide B accession
Q6NZY4
Peptide A residue number
56
Peptide B residue number
56
Ligandability
7s7b F 229 F 242
A redox-regulated disulphide may form within Zinc finger CCHC domain-containing protein 8 between cysteines 229 and 242.
Details
Redox score ?
91
PDB code
7s7b
Structure name
human nuclear exosome targeting (next) complex homodimer bound to rna (substrate 1)
Structure deposition date
2021-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
34
Minimum pKa ?
7
% buried
0
Peptide accession
Q6NZY4
Residue number A
229
Residue number B
242
Peptide name
Zinc finger CCHC domain-containing protein 8
Ligandability
Cysteine 229 of Zinc finger CCHC domain-containing protein 8
Cysteine 242 of Zinc finger CCHC domain-containing protein 8
7s7b F 229 F 232
A redox-regulated disulphide may form within Zinc finger CCHC domain-containing protein 8 between cysteines 229 and 232.
Details
Redox score ?
87
PDB code
7s7b
Structure name
human nuclear exosome targeting (next) complex homodimer bound to rna (substrate 1)
Structure deposition date
2021-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
34
Minimum pKa ?
7
% buried
0
Peptide accession
Q6NZY4
Residue number A
229
Residue number B
232
Peptide name
Zinc finger CCHC domain-containing protein 8
Ligandability
Cysteine 229 of Zinc finger CCHC domain-containing protein 8
Cysteine 232 of Zinc finger CCHC domain-containing protein 8
7s7b B 232 B 242
A redox-regulated disulphide may form within Zinc finger CCHC domain-containing protein 8 between cysteines 232 and 242.
Details
Redox score ?
87
PDB code
7s7b
Structure name
human nuclear exosome targeting (next) complex homodimer bound to rna (substrate 1)
Structure deposition date
2021-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
34
Minimum pKa ?
9
% buried
0
Peptide accession
Q6NZY4
Residue number A
232
Residue number B
242
Peptide name
Zinc finger CCHC domain-containing protein 8
Ligandability
Cysteine 232 of Zinc finger CCHC domain-containing protein 8
Cysteine 242 of Zinc finger CCHC domain-containing protein 8
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