ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

IQGAP1 protein

Intramolecular
Cysteine 148 and cysteine 151
A redox-regulated disulphide may form within IQGAP1 protein between cysteines 148 and 151. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
2rr8
Structure name
solution structure of calponin homology domain of iqgap1
Structure deposition date
2010-06-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
77
Minimum pKa ?
13
% buried
97
Peptide accession
Q6P1N4
Residue number A
148
Residue number B
151
Peptide name
IQGAP1 protein

Ligandability

Cysteine 148 of IQGAP1 protein

Cysteine 151 of IQGAP1 protein

If this tool was useful for finding a disulphide, please cite: