ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

ATPase family AAA domain-containing protein 2

Intramolecular
Cysteine 1057 and cysteine 1079
A redox-regulated disulphide may form within ATPase family AAA domain-containing protein 2 between cysteines 1057 and 1079.

Details

Redox score ?
68
PDB code
5a82
Structure name
crystal structure of human atad2 bromodomain in complex with 4-(3r,4r)-4-(3-methyl-2-oxo-1,2-dihydro-1,7- naphthyridin-8-yl)aminopiperidin-3-yloxymethyl)-1-thiane-1, 1-dione
Structure deposition date
2015-07-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
9
% buried
32
Peptide accession
Q14CR1
Residue number A
1057
Residue number B
1079
Peptide name
ATPase family AAA domain-containing protein 2

Ligandability

Cysteine 1057 of ATPase family AAA domain-containing protein 2

Cysteine 1079 of ATPase family AAA domain-containing protein 2

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