a tool for identifying drug-targetable redox-active disulphides

Coronin-6

Intramolecular

Cysteine 40 and cysteine 344

A redox-regulated disulphide may form within Coronin-6 between cysteines 40 and 344.

Details

Redox score ?

63

PDB code

Structure name

crystal structure of human coro6

Structure deposition date

2020-12-09

Thiol separation (Å)

5

Half-sphere exposure sum ?

90

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

40

Residue number B

344

Peptide name

Coronin-6

Ligandability

Cysteine 40 of Coronin-6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 344 of Coronin-6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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