ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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C-type lectin domain family 2 member A

Intramolecular
Cysteine 58 and cysteine 69
Cysteine 86 and cysteine 167
A redox-regulated disulphide may form within C-type lectin domain family 2 member A between cysteines 58 and 69.

Details

Redox score ?
86
PDB code
4iop
Structure name
crystal structure of nkp65 bound to its ligand kacl
Structure deposition date
2013-01-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6UVW9
Residue number A
58
Residue number B
69
Peptide name
C-type lectin domain family 2 member A

Ligandability

Cysteine 58 of C-type lectin domain family 2 member A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 69 of C-type lectin domain family 2 member A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within C-type lectin domain family 2 member A between cysteines 86 and 167.

Details

Redox score ?
82
PDB code
4iop
Structure name
crystal structure of nkp65 bound to its ligand kacl
Structure deposition date
2013-01-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6UVW9
Residue number A
86
Residue number B
167
Peptide name
C-type lectin domain family 2 member A

Ligandability

Cysteine 86 of C-type lectin domain family 2 member A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 167 of C-type lectin domain family 2 member A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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