a tool for identifying drug-targetable redox-active disulphides

Glycerophosphocholine cholinephosphodiesterase ENPP6

Intramolecular

Cysteine 142 and cysteine 154

A redox-regulated disulphide may form within Glycerophosphocholine cholinephosphodiesterase ENPP6 between cysteines 142 and 154.

Details

Redox score ?

84

PDB code

Structure name

structure of enpp6, a choline-specific glycerophosphodiester- phosphodiesterase

Structure deposition date

2015-10-27

Thiol separation (Å)

2

Half-sphere exposure sum ?

67

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

142

Residue number B

154

Peptide name

Glycerophosphocholine cholinephosphodiesterase ENPP6

Ligandability

Cysteine 142 of Glycerophosphocholine cholinephosphodiesterase ENPP6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 154 of Glycerophosphocholine cholinephosphodiesterase ENPP6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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