ALK and LTK ligand 2
Intramolecular
Cysteine 111 and cysteine 147
Cysteine 125 and cysteine 134
Cysteine 783 and cysteine 147
Cysteine 688 and cysteine 701
Cysteine 906 and cysteine 928
7nwz C 111 C 147
A redox-regulated disulphide may form within ALK and LTK ligand 2 between cysteines 111 and 147.
Details
Redox score ?
90
PDB code
7nwz
Structure name
alk:alkal2 complex
Structure deposition date
2021-03-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6UX46
Residue number A
111
Residue number B
147
Peptide name
ALK and LTK ligand 2
Ligandability
Cysteine 111 of ALK and LTK ligand 2
Cysteine 147 of ALK and LTK ligand 2
7nwz C 125 C 134
A redox-regulated disulphide may form within ALK and LTK ligand 2 between cysteines 125 and 134.
Details
Redox score ?
84
PDB code
7nwz
Structure name
alk:alkal2 complex
Structure deposition date
2021-03-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6UX46
Residue number A
125
Residue number B
134
Peptide name
ALK and LTK ligand 2
Ligandability
Cysteine 125 of ALK and LTK ligand 2
Cysteine 134 of ALK and LTK ligand 2
7ls0 D 783 D 794
A redox-regulated disulphide may form within ALK and LTK ligand 2 between cysteines 783 and 147 (783 and 794 respectively in this structure).
Details
Redox score ?
81
PDB code
7ls0
Structure name
structure of the human alk grd bound to aug
Structure deposition date
2021-02-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6UX46
Residue number A
783
Residue number B
147
Peptide name
ALK and LTK ligand 2
Ligandability
Cysteine 783 of ALK and LTK ligand 2
Cysteine 147 of ALK and LTK ligand 2
Cysteine 783 in protein A could not be asigned to a Uniprot residue.
7ls0 B 688 B 701
A redox-regulated disulphide may form within ALK and LTK ligand 2 between cysteines 688 and 701.
Details
Redox score ?
nan
PDB code
7ls0
Structure name
structure of the human alk grd bound to aug
Structure deposition date
2021-02-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6UX46
Residue number A
688
Residue number B
701
Peptide name
ALK and LTK ligand 2
Ligandability
Cysteine 688 of ALK and LTK ligand 2
Cysteine 701 of ALK and LTK ligand 2
Cysteine 688 in protein A could not be asigned to a Uniprot residue.
Cysteine 701 in protein B could not be asigned to a Uniprot residue.
7ls0 B 906 B 928
A redox-regulated disulphide may form within ALK and LTK ligand 2 between cysteines 906 and 928.
Details
Redox score ?
nan
PDB code
7ls0
Structure name
structure of the human alk grd bound to aug
Structure deposition date
2021-02-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
116
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6UX46
Residue number A
906
Residue number B
928
Peptide name
ALK and LTK ligand 2
Ligandability
Cysteine 906 of ALK and LTK ligand 2
Cysteine 928 of ALK and LTK ligand 2
Cysteine 906 in protein A could not be asigned to a Uniprot residue.
Cysteine 928 in protein B could not be asigned to a Uniprot residue.
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