ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Interleukin-20 receptor subunit beta

Intramolecular
Cysteine 89 and cysteine 97
Cysteine 202 and cysteine 223
A redox-regulated disulphide may form within Interleukin-20 receptor subunit beta between cysteines 89 and 97.

Details

Redox score ?
86
PDB code
4doh
Structure name
il20/il201/il20r2 ternary complex
Structure deposition date
2012-02-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6UXL0
Residue number A
89
Residue number B
97
Peptide name
Interleukin-20 receptor subunit beta

Ligandability

Cysteine 89 of Interleukin-20 receptor subunit beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 97 of Interleukin-20 receptor subunit beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Interleukin-20 receptor subunit beta between cysteines 202 and 223.

Details

Redox score ?
82
PDB code
6df3
Structure name
crystal structure of ternary complex of il-24 with soluble receptors il-22ra and il-20rb
Structure deposition date
2018-05-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6UXL0
Residue number A
202
Residue number B
223
Peptide name
Interleukin-20 receptor subunit beta

Ligandability

Cysteine 202 of Interleukin-20 receptor subunit beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 223 of Interleukin-20 receptor subunit beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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