Germ cell-specific gene 1-like protein
Intermolecular
Cysteine 220 and cysteine 220
Cysteine 33 and cysteine 33
Cysteine 33 and cysteine 220
Intramolecular
Cysteine 99 and cysteine 110
Cysteine 33 and cysteine 220
Cysteine 219 and cysteine 220
Cysteine 211 and cysteine 211
Cysteine 33 and cysteine 89
Cysteine 718 and cysteine 211
5wen A 315 B 315
A redox-regulated disulphide may form between two units of Germ cell-specific gene 1-like protein at cysteines 220 and 220 (315 and 315 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
5wen
Structure name
glua2 bound to gsg1l in digitonin, state 2
Structure deposition date
2017-07-10
Thiol separation (Å)
7
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide A name
Germ cell-specific gene 1-like protein
Peptide B name
Germ cell-specific gene 1-like protein
Peptide A accession
D3Z7H4
Peptide B accession
D3Z7H4
Peptide A residue number
220
Peptide B residue number
220
Ligandability
5vhy A 63 B 63
A redox-regulated disulphide may form between two units of Germ cell-specific gene 1-like protein at cysteines 33 and 33 (63 and 63 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
5vhy
Structure name
glua2-2xgsg1l bound to zk
Structure deposition date
2017-04-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide A name
Germ cell-specific gene 1-like protein
Peptide B name
Germ cell-specific gene 1-like protein
Peptide A accession
D3ZK93
Peptide B accession
D3ZK93
Peptide A residue number
33
Peptide B residue number
33
Ligandability
5vhy C 63 D 315
A redox-regulated disulphide may form between two units of Germ cell-specific gene 1-like protein at cysteines 33 and 220 (63 and 315 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
5vhy
Structure name
glua2-2xgsg1l bound to zk
Structure deposition date
2017-04-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide A name
Germ cell-specific gene 1-like protein
Peptide B name
Germ cell-specific gene 1-like protein
Peptide A accession
D3ZK93
Peptide B accession
D3ZK93
Peptide A residue number
33
Peptide B residue number
220
Ligandability
Cysteine 33 of Germ cell-specific gene 1-like protein
Cysteine 220 of Germ cell-specific gene 1-like protein
5wen A 1099 A 1110
A redox-regulated disulphide may form within Germ cell-specific gene 1-like protein between cysteines 99 and 110 (1099 and 1110 respectively in this structure).
Details
Redox score ?
86
PDB code
5wen
Structure name
glua2 bound to gsg1l in digitonin, state 2
Structure deposition date
2017-07-10
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
D3Z7H4
Residue number A
99
Residue number B
110
Peptide name
Germ cell-specific gene 1-like protein
Ligandability
Cysteine 99 of Germ cell-specific gene 1-like protein
Cysteine 110 of Germ cell-specific gene 1-like protein
5wek A 63 A 315
A redox-regulated disulphide may form within Germ cell-specific gene 1-like protein between cysteines 33 and 220 (63 and 315 respectively in this structure).
Details
Redox score ?
82
PDB code
5wek
Structure name
glua2 bound to antagonist zk and gsg1l in digitonin, state 1
Structure deposition date
2017-07-10
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
D3Z7H4
Residue number A
33
Residue number B
220
Peptide name
Germ cell-specific gene 1-like protein
Ligandability
Cysteine 33 of Germ cell-specific gene 1-like protein
Cysteine 220 of Germ cell-specific gene 1-like protein
5vhx E 218 E 219
A redox-regulated disulphide may form within Germ cell-specific gene 1-like protein between cysteines 219 and 220 (218 and 219 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
5vhx
Structure name
glua2-1xgsg1l bound to zk
Structure deposition date
2017-04-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
83
Minimum pKa ?
10
% buried
66
Peptide accession
D3ZK93
Residue number A
219
Residue number B
220
Peptide name
Germ cell-specific gene 1-like protein
Ligandability
Cysteine 219 of Germ cell-specific gene 1-like protein
Cysteine 220 of Germ cell-specific gene 1-like protein
5wem A 528 A 1211
A redox-regulated disulphide may form within Germ cell-specific gene 1-like protein between cysteines 211 and 211 (528 and 1211 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
5wem
Structure name
glua2 bound to gsg1l in digitonin, state 1
Structure deposition date
2017-07-10
Thiol separation (Å)
10
Half-sphere exposure sum ?
52
Minimum pKa ?
10
% buried
54
Peptide accession
D3Z7H4
Residue number A
211
Residue number B
211
Peptide name
Germ cell-specific gene 1-like protein
Ligandability
Cysteine 211 of Germ cell-specific gene 1-like protein
Cysteine 211 of Germ cell-specific gene 1-like protein
5wen C 63 C 89
A redox-regulated disulphide may form within Germ cell-specific gene 1-like protein between cysteines 33 and 89 (63 and 89 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
28
PDB code
5wen
Structure name
glua2 bound to gsg1l in digitonin, state 2
Structure deposition date
2017-07-10
Thiol separation (Å)
10
Half-sphere exposure sum ?
76
Minimum pKa ?
13
% buried
nan
Peptide accession
D3Z7H4
Residue number A
33
Residue number B
89
Peptide name
Germ cell-specific gene 1-like protein
Ligandability
Cysteine 33 of Germ cell-specific gene 1-like protein
Cysteine 89 of Germ cell-specific gene 1-like protein
Cysteine 89 in protein B could not be asigned to a Uniprot residue.
5wek C 718 C 773
A redox-regulated disulphide may form within Germ cell-specific gene 1-like protein between cysteines 718 and 211 (718 and 773 respectively in this structure).
Details
Redox score ?
nan
PDB code
5wek
Structure name
glua2 bound to antagonist zk and gsg1l in digitonin, state 1
Structure deposition date
2017-07-10
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
D3Z7H4
Residue number A
718
Residue number B
211
Peptide name
Germ cell-specific gene 1-like protein
Ligandability
Cysteine 718 of Germ cell-specific gene 1-like protein
Cysteine 211 of Germ cell-specific gene 1-like protein
Cysteine 718 in protein A could not be asigned to a Uniprot residue.
Uncertain whether structure cysteine 773 has been assigned to correct residue.
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