Interleukin-34
Intramolecular
Cysteine 177 and cysteine 191
Cysteine 35 and cysteine 180
Cysteine 35 and cysteine 179
Cysteine 179 and cysteine 180
Cysteine 180 and cysteine 191
Cysteine 177 and cysteine 180
Cysteine 35 and cysteine 191
Cysteine 35 and cysteine 177
Cysteine 179 and cysteine 191
Cysteine 177 and cysteine 179
4exn A 177 A 191
A redox-regulated disulphide may form within Interleukin-34 between cysteines 177 and 191.
Details
Redox score ?
89
PDB code
4exn
Structure name
crystal structure of mouse interleukin-34
Structure deposition date
2012-04-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8R1R4
Residue number A
177
Residue number B
191
Peptide name
Interleukin-34
Ligandability
Cysteine 177 of Interleukin-34
Cysteine 191 of Interleukin-34
4dkd B 35 B 180
A redox-regulated disulphide may form within Interleukin-34 between cysteines 35 and 180.
Details
Redox score ?
86
PDB code
4dkd
Structure name
crystal structure of human interleukin-34 bound to human csf-1r
Structure deposition date
2012-02-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6ZMJ4
Residue number A
35
Residue number B
180
Peptide name
Interleukin-34
Ligandability
Cysteine 35 of Interleukin-34
Cysteine 180 of Interleukin-34
4dkf A 35 A 179
A redox-regulated disulphide may form within Interleukin-34 between cysteines 35 and 179.
Details
Redox score ?
70
PDB code
4dkf
Structure name
crystal structure of human interleukin-34 bound to fab2
Structure deposition date
2012-02-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
9
% buried
nan
Peptide accession
Q6ZMJ4
Residue number A
35
Residue number B
179
Peptide name
Interleukin-34
Ligandability
Cysteine 35 of Interleukin-34
Cysteine 179 of Interleukin-34
4dkc A 179 A 180
A redox-regulated disulphide may form within Interleukin-34 between cysteines 179 and 180.
Details
Redox score ?
70
PDB code
4dkc
Structure name
crystal structure of human interleukin-34
Structure deposition date
2012-02-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
9
% buried
nan
Peptide accession
Q6ZMJ4
Residue number A
179
Residue number B
180
Peptide name
Interleukin-34
Ligandability
Cysteine 179 of Interleukin-34
Cysteine 180 of Interleukin-34
4dkd B 180 B 191
A redox-regulated disulphide may form within Interleukin-34 between cysteines 180 and 191. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
4dkd
Structure name
crystal structure of human interleukin-34 bound to human csf-1r
Structure deposition date
2012-02-03
Thiol separation (Å)
8
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6ZMJ4
Residue number A
180
Residue number B
191
Peptide name
Interleukin-34
Ligandability
Cysteine 180 of Interleukin-34
Cysteine 191 of Interleukin-34
4dkd B 177 B 180
A redox-regulated disulphide may form within Interleukin-34 between cysteines 177 and 180. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
4dkd
Structure name
crystal structure of human interleukin-34 bound to human csf-1r
Structure deposition date
2012-02-03
Thiol separation (Å)
8
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6ZMJ4
Residue number A
177
Residue number B
180
Peptide name
Interleukin-34
Ligandability
Cysteine 177 of Interleukin-34
Cysteine 180 of Interleukin-34
4dkd B 35 B 191
A redox-regulated disulphide may form within Interleukin-34 between cysteines 35 and 191. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
4dkd
Structure name
crystal structure of human interleukin-34 bound to human csf-1r
Structure deposition date
2012-02-03
Thiol separation (Å)
10
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6ZMJ4
Residue number A
35
Residue number B
191
Peptide name
Interleukin-34
Ligandability
Cysteine 35 of Interleukin-34
Cysteine 191 of Interleukin-34
4dkf A 35 A 177
A redox-regulated disulphide may form within Interleukin-34 between cysteines 35 and 177. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
4dkf
Structure name
crystal structure of human interleukin-34 bound to fab2
Structure deposition date
2012-02-03
Thiol separation (Å)
10
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q6ZMJ4
Residue number A
35
Residue number B
177
Peptide name
Interleukin-34
Ligandability
Cysteine 35 of Interleukin-34
Cysteine 177 of Interleukin-34
4dkc A 179 A 191
A redox-regulated disulphide may form within Interleukin-34 between cysteines 179 and 191. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
4dkc
Structure name
crystal structure of human interleukin-34
Structure deposition date
2012-02-03
Thiol separation (Å)
10
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
nan
Peptide accession
Q6ZMJ4
Residue number A
179
Residue number B
191
Peptide name
Interleukin-34
Ligandability
Cysteine 179 of Interleukin-34
Cysteine 191 of Interleukin-34
4dkc B 177 B 179
A redox-regulated disulphide may form within Interleukin-34 between cysteines 177 and 179. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
4dkc
Structure name
crystal structure of human interleukin-34
Structure deposition date
2012-02-03
Thiol separation (Å)
10
Half-sphere exposure sum ?
52
Minimum pKa ?
9
% buried
nan
Peptide accession
Q6ZMJ4
Residue number A
177
Residue number B
179
Peptide name
Interleukin-34
Ligandability
Cysteine 177 of Interleukin-34
Cysteine 179 of Interleukin-34
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