ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Tripartite motif-containing protein 72

Intramolecular
Cysteine 313 and cysteine 456
A redox-regulated disulphide may form within Tripartite motif-containing protein 72 between cysteines 313 and 456. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
3kb5
Structure name
pry-spry domain of human trim72
Structure deposition date
2009-10-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
71
Minimum pKa ?
11
% buried
70
Peptide accession
Q6ZMU5
Residue number A
313
Residue number B
456
Peptide name
Tripartite motif-containing protein 72

Ligandability

Cysteine 313 of Tripartite motif-containing protein 72

Cysteine 456 of Tripartite motif-containing protein 72

If this tool was useful for finding a disulphide, please cite: