a tool for identifying drug-targetable redox-active disulphides

Fc receptor-like A

Intramolecular

Cysteine 192 and cysteine 240

A redox-regulated disulphide may form within Fc receptor-like A between cysteines 192 and 240 (209 and 257 respectively in this structure).

Details

Redox score ?

83

PDB code

Structure name

crystal structure of the second ig-c2 domain of human fc-receptor like a (fcrla), isoform 9 [nysgrc-005836]

Structure deposition date

2012-11-08

Thiol separation (Å)

2

Half-sphere exposure sum ?

82

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

192

Residue number B

240

Peptide name

Fc receptor-like A

Ligandability

Cysteine 192 of Fc receptor-like A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 240 of Fc receptor-like A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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