Ras-related GTP-binding protein A
Intramolecular
Cysteine 157 and cysteine 159
Cysteine 124 and cysteine 157
Cysteine 124 and cysteine 159
Cysteine 109 and cysteine 124
Cysteine 63 and cysteine 109
6s6a B 157 B 159
A redox-regulated disulphide may form within Ras-related GTP-binding protein A between cysteines 157 and 159.
Details
Redox score ?
81
PDB code
6s6a
Structure name
crystal structure of raga-q66l/ragc-t90n gtpase heterodimer complex
Structure deposition date
2019-07-02
Thiol separation (Å)
4
Half-sphere exposure sum ?
78
Minimum pKa ?
3
% buried
94
Peptide accession
Q7L523
Residue number A
157
Residue number B
159
Peptide name
Ras-related GTP-binding protein A
Ligandability
Cysteine 157 of Ras-related GTP-binding protein A
Cysteine 159 of Ras-related GTP-binding protein A
6s6a B 124 B 157
A redox-regulated disulphide may form within Ras-related GTP-binding protein A between cysteines 124 and 157.
Details
Redox score ?
78
PDB code
6s6a
Structure name
crystal structure of raga-q66l/ragc-t90n gtpase heterodimer complex
Structure deposition date
2019-07-02
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
3
% buried
94
Peptide accession
Q7L523
Residue number A
124
Residue number B
157
Peptide name
Ras-related GTP-binding protein A
Ligandability
Cysteine 124 of Ras-related GTP-binding protein A
Cysteine 157 of Ras-related GTP-binding protein A
6s6d B 124 B 159
A redox-regulated disulphide may form within Ras-related GTP-binding protein A between cysteines 124 and 159. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
6s6d
Structure name
crystal structure of raga-q66l-gtp/ragc-s75n-gdp gtpase heterodimer complex
Structure deposition date
2019-07-02
Thiol separation (Å)
4
Half-sphere exposure sum ?
85
Minimum pKa ?
14
% buried
100
Peptide accession
Q7L523
Residue number A
124
Residue number B
159
Peptide name
Ras-related GTP-binding protein A
Ligandability
Cysteine 124 of Ras-related GTP-binding protein A
Cysteine 159 of Ras-related GTP-binding protein A
6nzd F 109 F 124
A redox-regulated disulphide may form within Ras-related GTP-binding protein A between cysteines 109 and 124. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
6nzd
Structure name
cryo-em structure of the lysosomal folliculin complex (flcn-fnip2- raga-ragc-ragulator)
Structure deposition date
2019-02-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
62
Minimum pKa ?
11
% buried
78
Peptide accession
Q7L523
Residue number A
109
Residue number B
124
Peptide name
Ras-related GTP-binding protein A
Ligandability
Cysteine 109 of Ras-related GTP-binding protein A
Cysteine 124 of Ras-related GTP-binding protein A
6s6a A 63 A 109
A redox-regulated disulphide may form within Ras-related GTP-binding protein A between cysteines 63 and 109. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
6s6a
Structure name
crystal structure of raga-q66l/ragc-t90n gtpase heterodimer complex
Structure deposition date
2019-07-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
84
Minimum pKa ?
13
% buried
100
Peptide accession
Q7L523
Residue number A
63
Residue number B
109
Peptide name
Ras-related GTP-binding protein A
Ligandability
Cysteine 63 of Ras-related GTP-binding protein A
Cysteine 109 of Ras-related GTP-binding protein A
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