a tool for identifying drug-targetable redox-active disulphides

MOB kinase activator 1B

Intramolecular

Cysteine 79 and cysteine 84

A redox-regulated disulphide may form within MOB kinase activator 1B between cysteines 79 and 84.

Details

Redox score ?

80

PDB code

Structure name

structure of full-length mob1b

Structure deposition date

2016-05-24

Thiol separation (Å)

4

Half-sphere exposure sum ?

59

Minimum pK_a ?

8

% buried

44

Peptide accession

Residue number A

79

Residue number B

84

Peptide name

MOB kinase activator 1B

Ligandability

Cysteine 79 of MOB kinase activator 1B

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 84 of MOB kinase activator 1B

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: